(See WARNINGS: Clinical Worsening and Suicide Risk, PRECAUTIONS: Information for Patients, and PRECAUTIONS: Pediatric Use.) Paxil (paroxetine hydrochloride) is an orally administered psychotropic drug. Each film‑coated tablet contains paroxetine hydrochloride equivalent to.
Study 2 was a flexible‑dose study comparing paroxetine (20 mg to 50 mg daily) and placebo. A third study, also flexible-dose comparing paroxetine (20 mg to 50 mg daily), did not demonstrate statistically significant superiority of Paxil over placebo on the Hamilton Rating Scale for Anxiety (HAM‑A) total score, the primary outcome. Paxil demonstrated statistically significant superiority over placebo on the Hamilton Rating Scale for Anxiety (HAM‑A) total score.
Patients randomized to paroxetine were significantly less likely to relapse than comparably treated patients who were randomized to placebo.
PAXIL (paroxetine hydrochloride) is an orally administered psychotropic drug. It is the hydrochloride salt of a phenylpiperidine compound.
The efficacy of PAXIL in the treatment of GAD was established in two 8-week placebo-controlled trials in adults with GAD. PAXIL has not been studied in children or adolescents with Generalized Anxiety Disorder (see Clinical Trials ).
PAXIL is indicated for the treatment of major depressive disorder.
Nevertheless, the physician who elects to use PAXIL for extended periods should periodically re-evaluate the long-term usefulness of the drug for the individual patient (see DOSAGE AND ADMINISTRATION ).
Find patient medical information for Paxil CR Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.
Otherwise, call a poison control center right away. US residents can call their local poison control center at. Canada residents can call a provincial poison control center. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Symptoms of overdose may include: irregular heartbeat, fainting, severe dizziness, seizures.
Some products that may interact with this drug include: thioridazine, other drugs that can cause bleeding/bruising (including antiplaet drugs such as clopidogrel, NSAIDs such as ibuprofen, " blood thinners " such as warfarin ).
It may take up to several weeks before you get the full benefit of this drug.
Keep all regular medical and psychiatric appointments.
Examples of affected drugs include atomoxetine, phenothiazines, pimozide, risperidone, tamoxifen, tetrabenazine, antiarrhythmics such as propafenone/ flecainide, TCA antidepressants such as desipramine / amitriptyline, among others.
Paroxetine, also known by the trade names Paxil and Seroxat among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class.
At the low dose used for menopausal hot flashes side effects are similar to placebo and dose tapering is not required for discontinuation. FDA approved low dose paroxetine for the treatment of moderate-to-severe vasomotor symptoms (e.g. Randomized controlled trials have shown modest relief in such cases. On June 28, 2013 U.S. hot flashes and night sweats) associated with menopause.
The United States Department of Justice fined GlaxoSmithKline $3 billion in 2012, including a sum for withholding data on paroxetine, unlawfully promoting it for under-18s and preparing an article, following one of its clinical trials, study 329, that misleadingly reported the drug was effective in treating adolescent depression.
Paxil (paroxetine) is an antidepressant belonging to a group of drugs called selective serotonin reuptake inhibitors (SSRIs). Paroxetine affects chemicals in the brain that may be unbalanced in people with depression, anxiety, or other disorders. Paxil is used to treat depression.
changes in weight or appetite;
CSA Schedule N Not a controlled drug.
Paroxetine can pass into breast milk and may cause side effects in the nursing baby. You should not breast-feed while using this medicine.
seizure medicine - phenobarbital, phenytoin.
Do not start or stop taking this medicine during pregnancy without your doctor's advice.
Do not use Paxil within 14 days before or 14 days after you have used an MAO inhibitor, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.
Be careful if you drive or do anything that requires you to be alert.